ESR Correction Formula:
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The ESR correction formula adjusts the erythrocyte sedimentation rate (ESR) for hematocrit (Hct) levels. This is important because hematocrit significantly affects ESR values - lower hematocrit leads to faster ESR.
The calculator uses the ESR correction formula:
Where:
Explanation: The formula accounts for the inverse relationship between hematocrit and ESR. The correction is particularly important in patients with anemia.
Details: Correcting ESR for hematocrit provides a more accurate assessment of inflammatory activity, especially in patients with abnormal hematocrit levels.
Tips: Enter ESR in mm/hr and hematocrit as a percentage. Note that the formula is not valid for hematocrit ≥55%.
Q1: Why correct ESR for hematocrit?
A: Hematocrit significantly affects ESR - lower hematocrit leads to faster ESR independent of inflammation.
Q2: When is correction most important?
A: Most important in anemic patients (Hct <40%) where uncorrected ESR may overestimate inflammation.
Q3: What are normal corrected ESR values?
A: Normal ranges vary by age and sex, but generally <20 mm/hr for men and <30 mm/hr for women.
Q4: Are there limitations to this correction?
A: The formula becomes invalid at Hct ≥55% and may not account for all factors affecting ESR.
Q5: Should corrected ESR replace standard ESR?
A: Corrected ESR should be interpreted alongside standard ESR and clinical context.