1. What is the RMI 1?

The Risk of Malignancy Index (RMI 1) is a scoring system used to assess the risk of ovarian cancer in women with pelvic masses. It combines ultrasound findings, menopausal status, and CA125 levels.

2. How Does the Calculator Work?

The calculator uses the RMI 1 equation:

Where:

• \( U \) — Ultrasound score (0-3)
• \( M \) — Menopausal status (1 = premenopausal, 3 = postmenopausal)
• \( CA125 \) — CA125 level in IU/mL

Interpretation:

• RMI < 25: Low risk
• RMI 25-250: Moderate risk
• RMI > 250: High risk

3. Importance of RMI Calculation

Details: The RMI helps guide clinical decisions about whether to refer patients to specialized oncology centers for further evaluation of ovarian masses.

4. Using the Calculator

Tips: Enter ultrasound score (0-3), select menopausal status, and enter CA125 level in IU/mL. All values must be valid.

5. Frequently Asked Questions (FAQ)

Q1: What are the ultrasound scoring criteria?
A: U=1 for each: multilocular cyst, solid areas, bilateral lesions, ascites, intra-abdominal metastases (max score 3).

Q2: How is menopausal status defined?
A: Postmenopausal = no periods for >1 year or age >50 with prior hysterectomy.

Q3: What is a normal CA125 level?
A: Typically <35 IU/mL, but levels can be elevated in many benign conditions.

Q4: Are there other RMI versions?
A: Yes, RMI 2-4 exist with different weightings, but RMI 1 remains widely used.

Q5: What's the sensitivity/specificity?
A: Sensitivity ~80%, specificity ~90% at cutoff of 200 for detecting ovarian cancer.