1. What is the RMI for Ovarian Cancer Risk?

The Risk of Malignancy Index (RMI) is a scoring system used to assess the risk of ovarian cancer in women with adnexal masses. It combines ultrasound findings, menopausal status, and CA125 levels to estimate malignancy risk.

2. How Does the Calculator Work?

The calculator uses the RMI equation:

Where:

• \( U \) — Ultrasound score (0-3)
• \( M \) — Menopausal status (1=premenopausal, 3=postmenopausal)
• \( CA125 \) — CA125 level in IU/mL

Explanation: The RMI helps differentiate between benign and malignant ovarian masses, with higher scores indicating greater risk of malignancy.

3. Importance of RMI Calculation

Details: RMI is crucial for triaging patients with ovarian masses, guiding decisions about referral to specialized centers, and determining appropriate management strategies.

4. Using the Calculator

Tips: Enter ultrasound score (0-3), select menopausal status, and provide CA125 level in IU/mL. All values must be valid (CA125 > 0).

5. Frequently Asked Questions (FAQ)

Q1: What do different RMI scores mean?
A: Scores ≥200 suggest high risk of malignancy and warrant specialist referral. Scores <25 have low malignancy risk.

Q2: How is the ultrasound score determined?
A: U=1 for one feature (multilocular cyst, solid areas, metastases, ascites, bilateral lesions). U=3 for multiple features.

Q3: What are normal CA125 levels?
A: Normal is generally <35 IU/mL, but levels can be elevated in many benign conditions.

Q4: Are there limitations to RMI?
A: RMI may be less accurate in premenopausal women and those with certain benign conditions that elevate CA125.

Q5: Should RMI replace clinical judgment?
A: No, RMI should be used in conjunction with clinical assessment and other diagnostic tools.