1. What is the RMI for Ovarian Cancer?

The Risk of Malignancy Index (RMI) is a scoring system used to assess the likelihood that an ovarian mass is malignant. It combines ultrasound findings, menopausal status, and CA125 levels to calculate a risk score.

2. How Does the Calculator Work?

The calculator uses the RMI formula:

Where:

• \( U \) — Ultrasound score (0-3)
• \( M \) — Menopausal status (1 = premenopausal, 3 = postmenopausal)
• \( CA125 \) — CA125 level in IU/mL

Ultrasound Score (U) Criteria:

• 0 - No ultrasound features of malignancy
• 1 - One ultrasound feature of malignancy
• 3 - Multiple ultrasound features of malignancy

3. Importance of RMI Calculation

Details: The RMI helps stratify patients into risk categories for ovarian cancer, guiding decisions about referral to specialist centers and further management.

4. Using the Calculator

Tips: Enter ultrasound score (0-3), select menopausal status, and enter CA125 level in IU/mL. All values must be valid (CA125 > 0).

5. Frequently Asked Questions (FAQ)

Q1: What are the RMI risk categories?
A: Low risk (<25), moderate risk (25-250), high risk (>250). Higher scores indicate greater likelihood of malignancy.

Q2: What ultrasound features are considered?
A: Multilocular cysts, solid areas, metastases, ascites, bilateral lesions.

Q3: How accurate is the RMI?
A: Sensitivity ~78%, specificity ~87% for detecting ovarian cancer when cutoff >200 is used.

Q4: Are there limitations to RMI?
A: Less accurate in premenopausal women and certain histologic types (e.g., mucinous tumors).

Q5: What's the next step if RMI is high?
A: Referral to gynecologic oncologist for further evaluation and possible surgery.